"The InstallShield Engine (iKernel.exe) could not be launched. No such interface supported" - Working Solution

By WireINPUT -
Check and Try this link, it might help:

http://consumerdocs.installshield.com/selfservice/viewContent.do?externalId=Q108497&sliceId=1


Example:
Q: I'm having a problem installing The Powerpuff Girls game. The installer starts
and then tells me "The InstallShield Engine (iKernel.exe) could not be launched.
No such interface supported".A: This error appears on some systems and is caused by a bug in the Installshield
software. In most cases, the installation can be completed by deleting the folder
C:\Program Files\Common Files\InstallShield\Engine. After deleting this folder, clear
it from the recycle bin (empty the recycle bin), and restart the installation.

http://www.annoyances.org/exec/forum/winxp/t1064933406

if the app is not compatible, we cannot do anything

if its an OS issue, then it should be problem with ikernel.exe and install shield

check and try these options.

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